Based on the 2015 Chinese 1% population survey, this study examines the spatial patterns of Chinese stem family and its influencing factors. It is found that there is significant heterogeneity among the distribution of stem families at the prefecture-level city with generally higher proportion of stem family in the south China and lower proportion in the north China. We further explore the spatial variation of factors affecting stem families using Geographic Weighted Regression (GWR) model. The results demonstrate that socioeconomic, demographic, and culture factors all play important roles in determining the distribution of stem families. The former two factors can exhibit opposite impact conditioned on the local culture and the development model of urbanization. Meanwhile, the impact of housing price is also divergent depending on the sensitivity of local housing market to the price change. These results suggest that the interplay of socioeconomic level, development mode, and cultural tradition ultimately shapes the pattern of Chinese stem family.